Digitized slide scanners have begun to revolutionize histology research. The Aperio CS2 slide scanner ushers in a new era of efficiency and accessibility unlocking a wealth of information previously hidden within traditional use of glass slides. The scanner creates high-resolution digital images, allowing researchers to view tissue samples on a computer screen. This eliminates the time previously dedicated to manual microscope stage navigation and targeted area identification. Now, high-resolution digital images can reveal intricate cellular structures, identify specific biomarkers, and even detect subtle changes in tissue composition over time. And, digital manipulation of images further streamlines analysis through effortless panning and zooming capabilities.
The Aperio CS2 addresses long-term challenges associated with physical slides. While traditional storage methods often lead to space constraints and deterioration of samples over time, the Aperio system digitizes slides, creating secure and readily accessible digital archives. The scanner also has the potential to facilitate seamless collaboration by enabling secure and effortless sharing of digital slides among colleagues worldwide. This simplified means of data sharing eliminates the need for physical glass slide shipment, accelerating the overall pace of research and discovery.
Quantifiable Data
Beyond streamlining workflow and creating storage solutions, the Aperio CS2 has the power to provide more objective, measurable data. Researchers can view and compare samples, regardless of size, to quantify the presence of specific markers.
Benefits for Larger Tissues Samples
- Macroscopic View: Researchers can analyze entire tissue samples simultaneously, helping them understand the overall architecture, boundaries between healthy and cancerous tissue, and the relationships between different tissue types.
- Spatial Context: The scanner allows visualization of different compartments within tissue, such as stroma, epithelium, and vasculature, providing a detailed picture of the tumor microenvironment.
- Tumor Heterogeneity: Detailed scans capture any diversity present within larger tumors, revealing variations in cell types, morphology, and genetic features.
Benefits for Smaller Tissues Samples
- High-Resolution Scans: Smaller tissue samples can be scanned at high resolution, revealing cellular details like nuclei, cell division stages, and subtle morphological changes.
- Quantitative Analysis: Precise measurements of features like tumor size and nuclear characteristics become feasible.
The Aperio CS2 scanner is also particularly powerful when combined with HistoSpring’s multiplexing capability services. Performing whole-slide imaging and multiplexing allows researchers to gain a more nuanced understanding of tumor biology. For example, histologists can identify and analyze multiple biomarkers within a single tissue sample, providing valuable insights into tumor cells’ complex interactions and dynamics. These insights could pave the way for advancements in various types of cancer research.
Additional Tools and Services
In addition to offering state of the art equipment to facilitate research studies, HistoSpring also performs all histological preparation for client samples, including sectioning, staining, scanning, and analysis, while also offering the following high-value services:
- Consultative Approach: Beyond processing samples, our consulting services include suggestions for next steps, recommendations for appropriate stains, and collaborative brainstorming research ideas.
- Data Interpretation: HistoSpring has experience with various staining techniques, which allows us to assist with the interpretation of data and provide additional insights into our clients’ research findings.
HistoSpring’s astuteness helps clients delve into detailed tissue analysis, accelerating advancements in research and ultimately improving patient outcomes. Hence, a fall blog post will provide exciting details about the intuitive new HALO AI image analysis software. When used with the Aperio CS2, HALO AI takes research one step further by enabling detailed analysis of digital images.
To learn more about HistoSpring’s comprehensive histology services and advanced suite of equipment, submit an inquiry here or email us at histology@histospring.com.
