The Importance of Leveraging Key Pieces of Equipment as a Life Science Start-Up: Part I

In the realm of wet lab environments, having access to key pieces of equipment is essential for both start-ups and academic researchers alike, propelling each group towards potential groundbreaking discoveries. Yet this vital equipment can be quite costly — and for many in the start-up life science space, the initial investment is beyond reach in those early stages.

In response, many organizations and academics in the life science research space have turned to laboratory incubators whose primary aim is to support a variety of scientific activities by providing affordable access to the necessary facilities, equipment, and resources.

In this two-part series, we’re getting a better understanding of all these important pieces of equipment and how leveraging a collaborative wet lab space is a smart decision for start-ups and academic researchers for a variety of reasons. Today, we’re focusing on two commonly required pieces of equipment, which include the Real-Time PCR Machine and the Plate Reader. And, a third piece of equipment, the Biological Irradiator to help researchers study radiation effects and biological responses.

Real-Time PCR (qPCR) Machine
A real-time PCR machine is a fundamental instrument that facilitates discoveries and advancements in the field of molecular research, across a wide range of applications. Nucleic acid amplification and detection techniques are among some of the most valuable biological research conducted today.

Real-time PCR can be used for both qualitative and quantitative analysis, which broadens its applicable reach, including:

  • Gene expression analysis
  • Genetic variation analysis
  • Gene mutation detection
  • microRNA and non-coding RNA analysis
  • Copy number variation
  • Drug metabolism enzymes
  • Protein expression
  • SNP genotyping

HistoSpring’s wet laboratory space is home to a Quant Studio real-time PCR machine, which is precise, versatile, and user-friendly. Access to this state of the art real-time PCR machine in a shared equipment setting is a cost-effective solution to ensure researchers have access to this technology without compromising the quality of their research testing.

The real-time PCR machine detects changes in gene expressions as low as 1.5-fold, and the system also includes the OptiFlex System, which improves overall data accuracy. The system also enables advanced multiplexing of multiple genes, accelerated thermal cycling, and rapid data analysis to reduce overall experimentation timelines. Thanks to its intuitive interface, this piece of equipment simplifies operation, so it is the perfect option for researchers of all skill levels.

Plate Reader
Finding the right plate reader can often feel like a daunting undertaking, especially because there are a lot of choices available on the market — and you need to find the right one to meet your lab’s specific needs, space requirements, and budget.

When utilizing HistoSpring’s wet lab space, you have access to the PerkinElmer VICTOR Nivo Plate Reader, the smallest plate reader on the market with all major detection technologies and a versatile tool that has the capability of offering a multitude of assays and offers a level of flexibility required for cutting-edge research. This compact and lightweight plate reader detects absorbance, luminescence, fluorescence intensity, and fluorescence polarization.

 It’s the ideal platform for everyday biochemical and cell-based assay research, that includes:

  • Kinetic measurements
  • Top and bottom reading
  • A 32-position filter storage system for measurements of differing wavelengths
  • An optional dispenser for the detection of fast responses and additional reagents
  • Temperature-controls
  • Optional gas control units to preserve the integrity of live-cell-based assays

Thanks to its rapid-reading capabilities, this plate reader enables researchers to analyze multiple samples efficiently, which is particularly valuable in studies that require large-scale screening or data collection efforts. Plus, the system’s intuitive software interface ensures operational ease and is designed for the FDA’s 21 CFR Part 11, which means researchers can focus on their intricate experiments as opposed to learning how to properly operate the instrument or worrying about formatting results for proper regulatory documentation.

Biological Irradiator
Because radiation testing plays such a pivotal role across various scientific disciplines to advance medical treatments and push forward innovative research, leveraging the right piece of equipment is essential. HistoSpring offers the RadSource RS 2000 Biological Irradiator, a leader in irradiation technology for precise control over radiation dosage and the enablement of targeted experiments for cancer biology, immunology, and genetics testing — all of which require accurate and reproducible results. This piece of equipment comes fully equipped with advanced safety features and compliance measures to make sure that all users can work with radiation safely and consistently.

Utilizing the RS 2000, start-ups can expedite their research and development endeavors, especially in domains where radiation holds significant importance, such as pharmaceuticals and biotechnology innovation. Accelerated irradiation processes can aid in proof-of-concept investigations, potentially enticing investors and collaborators.

In addition, the RadSource RS 2000 Biological Irradiator stands out for its precision, adaptability, and safety protocols, making it a groundbreaking instrument that empowers scientists, entrepreneurs, and incubators to carry out experiments that require radiation testing.

How HistoSpring Drives Scientific Progress with Advanced Equipment
HistoSpring offers innovative lab equipment to help drive scientific progress at their shared wet lab space. These key pieces of equipment come together to create an environment fully conducive to innovation and collaboration. By embracing this shared space, researchers gain more than just access to equipment—they become part of a vibrant community dedicated to advancing scientific knowledge and driving meaningful discoveries forward. Plus, the facility’s academic and clinical connections continue to foster knowledge exchange and partnerships, amplifying the impact of scientific endeavors beyond the New England area.

Stay tuned for the second part of this blog series and the other crucial pieces of equipment that are essential to life science research.

Learn more about HistoSpring’s shared wet laboratory space by filling out this form to get started.